MethodsThis research retrospective analyzed the connection between clinicopathological factors and clinical outcome（recurrence, canceration, recurrence-free success, and canceration-free survival） in 148 clients undergoing medical procedures in Chongqing General Hospital from 2014 to 2017. ResultsThe five-year total recurrence price had been 14.86% and the total non-antibiotic treatment recurrence rate was 8.78%. Univariate analysis showed that smoking index, laryngopharyngeal reflux and lesion range had been notably connected with recurrence（P less then 0.05）, and smoking index and lesion range were substantially linked with canceration（P less then 0.05）. Multivariate logistic regression analysis showed that cigarette smoking list ≥600 and laryngopharyngeal reflux had been independent threat factors for recurrence（P less then 0.05）, and smoking list ≥600 and lesion range ≥1/2 vocal cord were independent threat facets for canceration（P less then 0.05）. The mean carcinogenesis period for the postoperative smoking cessation group ended up being significantly longer（P less then 0.05）. ConclusionExcessive smoking, laryngopharyngeal reflux and an array of lesions could be regarding postoperative recurrence or cancerous progression of precancerous lesions in the vocal cord, and additional large-scale multi-center prospective randomized managed studies are needed to simplify the results of the preceding facets on recurrence and malignant alterations in the future.ObjectiveTo determine the effectiveness of individualized vocals therapy in persistent pediatric vocals problems. PracticesThirty-eight kids have been accepted into the division of Pediatric Otolaryngology Shenzhen Hospital, Southern Medical University due to persistent vocals disorder from November 2021 to October 2022 had been included. All kiddies had been evaluated by powerful laryngoscopy before sound treatment. Two vocals physicians done GRBAS score and acoustic evaluation from the kids’ vocals samples to obtain the relevant variables including F0, Jitter, Shimmer, and MPT; All young ones were given personalized vocals treatment for 2 months. ResultsAmong 38 young ones with sound conditions, 75.8percent（29 situations） were diagnosed with vocal nodules, 20.6percent（8 cases） were vocal polyps, and 3.4%（1 case） were vocal cysts. And in all kiddies. And 51.7%（20 cases） had the sign of supraglottic extrusion under powerful laryngoscopy. GRBAS scores diminished from 1.93 ± 0.62, 1.82 ± 0.55, 0.98 ± 0.54, 0.65 ± 0.48, 1.05 ± 0.52 to 0.62 ± 0.60, 0.58 ± 0.53, 0.32 ± 0.40, 0.22 ± 0.36, 0.37 ± 0.36. F0, Jitter, Shimmer reduced from（243.11±39.73） Hz, （0.85±0.99）%, （9.96±3.78）% to（225.43±43.20） Hz, （0.33±0.57）%, （7.72±4.32）%, correspondingly MPT was https://www.selleckchem.com/products/ar-c155858.html prolonged from（5.82±2.30） s to（7.87±3.21） s after treatment. All parameters changes had statistical value. ConclusionVoice therapy can solve kid’s sound issues, boost their vocals high quality and efficiently treat youngsters’ sound disorders.ObjectiveTo analyze the significance and factors influencing of CT scan beneath the changed Valsalva maneuver. MethodsClinical data of 52 patients with hypopharyngeal carcinoma identified from August 2021 to December 2022 had been collected, all customers had calm breathing CT scan and modified Valsalva maneuver CT scan. Compare the exposure aftereffect of eye infections the aryepiglottic fold, interarytenoid fold, postcricoid location, piriform fossa apex, posterior hypopharyngeal wall surface, and glottis with each CT scanning strategy. The effects of age, throat circumference, throat length, BMI, tumor web site, and T stage from the visibility result had been reviewed. ResultsIn 52 patients, 50 patients（96.15%） finished CT scan at a time time. The publicity aftereffect of the CT scan under customized Valsalva maneuver within the aryepiglottic fold, interarytenoid fold, postcricoid area, piriform fossa apex, posterior hypopharyngeal wall was somewhat better than CT scan under calm breathing（Z=-4.002, -8.026, -8.349, -7.781, -8.608, all P less then 0.01）, while CT scan under customized Valsalva maneuver ended up being substantially worse in glottis than CT scan under calm breathing（Z=-3.625, P less then 0.01）. When you look at the customized Valsalva CT scan, age had no apparent impact on the exposure effect. The exposure effect had been better with long-neck length, smaller neck circumference, smaller BMI and smaller T stage. The publicity of postcricoid carcinoma ended up being much better than pyriform sinus carcinoma and posterior hypopharyngeal wall carcinoma. But variations are not all statistically significant. ConclusionThe anatomical framework of the hypopharynx was obviously under CT scan with modified Valsalva maneuver, which clinical application is easy, but the effectation of glottis had been worse. The influence of age, neck circumference, neck size, BMI, and cyst T stage on the exposure impact nevertheless needs more investigation.〓 Goals To analyze the pathological and clinical attributes of nasal breathing epithelial adenomatoid hamartoma（REAH）, and review the diagnostic things, to enhance the knowledge of diagnosis and therapy. MethodsThe medical data of 16 customers with REAH had been analyzed retrospectively. The clinical manifestations, pathological features, imaging features, surgical treatment and prognosis were summarized. Results16 cases of REAH had been examined, 10 cases（62.50%） were involving sinusitis, 1 case（6.25%） had been related to inverted papilloma, 1 case（6.25%） ended up being connected with hemangioma. 5 cases（31.25%） had a history of nasal sinus surgery, including 1 instance with 3 times of nasal sinus surgery, 1 situation with twice of nasal sinus surgery, 3 cases with one time of nasal sinus surgery; 10 cases（62.50%） occurred in the bilateral olfactory cleft, 2 cases（12.50%） when you look at the unilateral olfactory cleft, 3 cases（18.75%） within the unilateral middle turbinate, 1 case（6.25%） within the nasopharynx. All 16 clients were pathologically identified as REAH. Into the patients with lesions based in bilateral olfactory fissures, shaped widening of olfactory fissures and horizontal displacement of middle turbinate were seen on preoperative sinus CT. The typical width of bilateral olfactory fissures had been （9.9±2.70） mm. The proportion of large to narrow olfactory cleft was 1.21 ± 0.19. There is no factor in Lund-Mackay score involving the two sides（P>0.05）. All patients underwent surgery under general anesthesia and nasal endoscopy. The follow-up duration ranged from 1 to 66 months, and no recurrence occurred.